Precursors of acyclovir ie, Beyond Simplex Review valacyclovir, famciclovir have bioavailability emend than that of their active metabolites acyclovir and penciclovir, respectively. The bioavailability of valacyclovir ranges from about 42-64%, while that of acyclovir is between 10-20%.
The spring of a multicenter, backward, band ponder present that loiter initiation of acyclovir therapy was combined with way greater strife of death in neonates with HSV infection.
Acyclovir Zovirax View full pharmaceutical information Inhibits liveliness of HSV-1 and HSV-2. Patients know least pain and fastest resolution of cutaneous lesions with immediate startle of therapeutics, for the most part within 48 h after cut attack. Selectively incorporated into disease cells. May prevent rolling outbreaks. Long record of use with excellent safeness outline.
Available as PO susp 200 mg/5 mL, tab, cap, enema, and topical devising. Topical conventionality does not seem to be effective in recurrent mucocutaneous or genital HSV infections and sacrifice no advantage over PO beauty in treating primary genital HSV infections. For obese patients, rate IV dose agreeing to ideal person heaviness.